THE HANDA RESEARCH GROUP
Publications
2024
more...coming soon....
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76. Ansari, R. N.; Choudhary, R. H.; Nachtegaal, M.; Clark, A. H.; Plummer, S. V.; Jasinki, J. B.; Gallou, F.; Handa, S. "Aminations of Aryl Halides Using Nitroaromatics as Coupling Partners: Overcoming Hydrodehalogenation Pathway Under Hydrogen Atmosphere in Water" ACS Catal. 2024, accepted.
75. Parmar, S.; Handa, S.; Kozlowski, P. M. "Mechanistic insights into photo-assisted DMF cleavage mediated by charge transfer reaction" J. Photochem. Photobiol., A 2024, 466, 115155.
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74. Virdi, J. K.; Dusunge, A.; Handa, S. "Aqueous Micelles as Solvent, Ligand, and Reaction Promotor" JACS Au 2024, ASAP, https://pubs.acs.org/doi/10.1021/jacsau.3c00605
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2023
73. Sharma, S.; Ansari, T.; Kaur, K.; Gorce, A.; Braje, W.; Handa, S. "Rapid Amide Couplings in Water for Undergraduate Laboratories" J. Chem. Educ., 2023, 100, 4406. https://doi.org/10.1021/acs.jchemed.3c00350
• Featured on the journal cover. https://pubs.acs.org/cms/10.1021/jceda8.2023.100.issue-11/asset/jceda8.2023.100.issue-11.xlargecover-2.jpg
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72. Hedouin, G.; Sharma, S.; Kaur, K.; Choudhary, R. H.; Jasinski, J. B.; Gallou, F.; Handa, S. "Ligand-Free Ultrasmall Recyclable Iridium(0) Nanoparticles for Regioselective Aromatic Hydrogenation of Phosphine Oxide Scaffolds: An Easy Access to New Phosphine Ligands" Angew. Chem. Int. Ed., 2023, 62, e20230713. https://doi.org/10.1002/anie.202307139
• Featured on the back cover of Angewandte. https://onlinelibrary.wiley.com/doi/epdf/10.1002/anie.202312348
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71. Handa, S. "VSI (Editorial): Sustainable Chemo- and Bio-Catalysis: From Academia to Industry "ACS Sustain. Chem. Eng., 2023, 11, 8404.
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70. Ansari, T.; Gallou, F.; Handa, S. "Palladium-catalyzed micellar cross-couplings " Coord. Chem. Rev., 2023, 488, 215158.
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69. Leahy, D. K.; Handa, S. "Nanocatalysis" Curr. Opin. Green Sustain. Chem. 2023, 41, 100814. https://doi.org/10.1016/j.cogsc.2023.100814
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68. Hedouin, G.; Ogulu, K.; Kaur, G.; Handa, S. "Aqueous Micellar Technology: An Alternative Beyond Organic Solvents " Chem. Commun. 2023, 59, 2842.
• Featured on the journal cover: https://pubs.rsc.org/en/content/articlepdf/2023/cc/d3cc90084c?page=search
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67. Sharma, S.; Braje, W.; Jasinski, J.; Handa, S. " Ultrasmall Cu(I) Nanoparticles Stabilized on Surface of HPMC: An Efficient Catalyst for Fast and Organic Solvent-Free Tandem Click Chemistry in Water" ChemSusChem 2023, 16, e202201826. https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cssc.202201826.
• Featured on the journal cover: https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cssc.202300053
• This article also appears in: Hot Topic: Click Chemistry - https://onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)1521-3773.hottopic-clickchemistry
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2022
66. Ansari, T.; Sharma, S.; Hazra, S.; Hicks, F.; Leahy, D. K.; Handa, S. "Trichloromethyl Carbanion in Aqueous Micelles: Mechanistic Insights and Access to Carboxylic Acids from (Hetero)aryl Halides" ACS Catal., 2022, 12, 15686. https://pubs.acs.org/doi/full/10.1021/acscatal.2c05288.
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65. Kaur, G.; Jasinski, J.; Gallou, F.; Handa, S. "Metal-Micelle Interaction Leading to Spontaneous Formation of Ligand-Free Palladium(0) Nanoparticles: Highly-Efficient Catalysis Enabling Biaryl Ketones Formation from Carboxylic Acid Derivatives" ACS Appl. Mater. Interfaces 2022, 14, 50947.
Featured on the journal cover of ASC Applied Materials and Interfaces.
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64. Sharma, S.; Parmar, P.; Ibrahim, F.; Clark, A. H.; Nachtegaal, N.; Jasinski, J. B.; Gallou, F.; Kozlowski, M. M.; Handa, S. "Sustainable and Bench-Stable Photoactive Aqueous Nanoaggregates of Cu(II) for ppm Level Cu(I) Catalysis in Water" Adv. Funct. Mater. 2022, 32, 2204459 (IF 18.8). https://doi.org/10.1002/adfm.202204459
• Featured on the journal cover.
https://onlinelibrary.wiley.com/doi/epdf/10.1002/adfm.202270202
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63. Bin, W.;‡ Miraghaee, S.;‡ Handa, S.; Gallou, F. "Nanocatalysis in Pharmaceutical Industry" Curr. Opin. Green Sustain. 2022, 38 (100691), 1-6.
https://doi.org/10.1016/j.cogsc.2022.100691
‡These authors contributed equally.
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62. Kaur, G.;‡ Kaur, K.‡ Handa, S. "Efficient Catalysis in Dynamic Nanomicelles Suspended in Water" Curr. Opin. Green Sustain. 2022, 38, 100690. https://doi.org/10.1016/j.cogsc.2022.100690
‡These authors contributed equally.
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61. Hedouin, G.; Hazra, S.; Gallou, F.; Handa, S. "The Catalytic Formation of Atropisomers and Stereocenters via Asymmetric Suzuki-Miyaura Couplings" ACS Catal. 2022, 12, 4918. https://doi.org/10.1021/acscatal.2c00933
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60. Hazra, S.; Gallou, F.; Handa, S. "Water: An Underestimated Solvent for Amide Bond-Forming Reactions" ACS Sustain. Chem. Eng. 2022, 10, 5299. https://doi.org/10.1021/acssuschemeng.2c00520
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59. Ogulu, D.;‡ Bora, P. P.;‡ Bihani, M.; Sharma, S.; Ansari, T. N.; Wilson, A. J.; Jasinski, J. B.; Gallou, F.; Handa, S. " Nanoparticles as Catalyst for Facile, General, Sustainable, and Highly Selective 1,4-Reductions in Aqueous Micelles" ACS Appl. Mater. Interfaces 2022, 14, 6754. https://doi.org/10.1021/acsami.1c22282
‡These authors contributed equally.
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2021
58. Hazra, S.; Seechurn, C. C. C. J.; Handa, S.; Colacot, T. "The Resurrection of Murahashi Coupling After Four Decades" ACS Catal., 2021, 11, 13118. https://doi.org/10.1021/acscatal.1c03564
Featured on the journal cover of ASC Catalysis.
https://pubs.acs.org/pb-assets/images/_journalCovers/accacs/accacs_v011i021-2.jpg?0.7890432926052785
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57. Sharma, S.; Ansari, T. N.; Handa, S. "HPMC: A Biomass-Based Semisynthetic Sustainable Additive Enabling Clean and Fast Chemistry in Water" ACS Sustain. Chem. Eng. 2021, 9, 12719. https://doi.org/10.1021/acssuschemeng.1c04607
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56. Ansari, T. N.; Sharma, S.; Hazra, S.; Jasinski, J.; Wilson, A. J.; Hicks, F.; Leahy, D. K.; Handa, S. "Shielding Effect of Nanomicelles: Stable and Catalytically Active Oxidizable Pd(0) Nanoparticle Catalyst Compatible for Cross-Couplings of Water-Sensitive Acid Chlorides in Water" JACS Au, 2021, 1, 1506. https://doi.org/10.1021/jacsau.1c00236
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55. Sharma, S.; Kaur, G.; Handa, S. "Insights into Fast Amide Couplings in Aqueous Nanomicelles " Org. Process Res. Dev. 2021, 25, 1960. https://doi.org/10.1021/acs.oprd.1c00203
Featured on the journal cover of OPRD.
https://pubs.acs.org/pb-assets/images/_journalCovers/oprdfk/oprdfk_v025i008-3.jpg?0.8430724340873964
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54. Ansari, T. N.;‡ Sharma, S.;‡ Bora, P. P.;‡ Ogulu, D.;‡ Parmar, S.; Gallou, F.; Kozlowski, P. M.; Handa, S. "Photoassisted Charge Transfer Between DMF and Substrate: Facile and Selective N,N-Dimethylamination of Fluoroarenes" ChemSusChem 2021, 14, 2704. https://doi.org/10.1002/cssc.202100761
‡These authors contributed equally.
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53. Hazra, S.; Kaur, G.; Handa, S. "Reactivity of Styrenes in Micelles: Safe, Selective, and Sustainable Functionalization with Azides and Carboxylic Acids" ACS Sustain. Chem. Eng. 2021, 9, 5513. https://doi.org/10.1021/acssuschemeng.1c01577
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52. Borlinghaus, N.; Ansari, T. N.; Braje, L.; Ogulu, D.; Handa, S.; Wittmann, V.; Braje, W. "Nucleophilic Aromatic Substitution Reactions under Aqueous, Mild Conditions Using Polymeric Additive HPMC" Green Chem. 2021, 23, 3955. https://doi.org/10.1039/D1GC00128K.
Featured on the journal cover of Green Chemistry.
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51. Duong, U.; Ansari, T.; Parmar, S.; Sharma, S.; Kozlowski, P.; Jasinski, J.; Plummer, S.; Gallou, F.; Handa, S. "Nanochannels in Photoactive Polymeric Cu(I) Compatible for Efficient micellar Catalysis: Sustainable Aerobic Oxidations of Alcohols in Water" ACS Sustain. Chem. Eng, 2021, 9, 2854.
https://pubs.acs.org/doi/10.1021/acssuschemeng.0c08792
Featured on the cover of ACS Sustain. Chem. Eng.
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50. Ansari, T. N.; Jasinski, J. B. Leahy, D. K.; Handa, S. "Metal-Micelle Cooperativity: Phosphine Ligand-Free Ultrasmall Palladium Nanoparticles for Catalysis in Water at Room Temperature" JACS Au, 2021, 1, 308.
https://doi.org/10.1021/jacsau.0c00087.
Featured on the front cover of JACS Au.
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2020
49. Petkova, D.; Borlinghaus, N.; Sharma, S, Kaschel, J.; Lindner, T.; Klee, J.; Haller, V.; Heitz, S.; Dietrich, J.; Braje, W.; Handa, S. "Hydrophobic Pockets of HPMC Enable Extremely Short Reaction Times in Water" ACS Sustain. Chem. Eng. 2020, 8, 12612.
•Feature in C&E News; see, https://cen.acs.org/synthesis/reagents/Food-additive-enables-fast-synthesis/98/web/2020/08
•Selected to be featured in ACS Editors' Choice
•Featured on the journal's cover
•Highlighted in OPRD, see:
https://pubs.acs.org/doi/10.1021/acs.oprd.0c00381
48. Sharma, S.; Buchbinder, N. W.; Braje, W. M.; Handa, S. "Fast Amide Couplings in Water: Extraction, Column Chromatography, and Crystallization Not Required" Org. Lett. 2020, 20, 5737. https://pubs.acs.org/doi/10.1021/acs.orglett.0c01676
•Highlighted in SYNFACTS, see: https://doi.org/10.1055/s-0040-1707369
•Highlighted in OPRD, see:
https://pubs.acs.org/doi/10.1021/acs.oprd.0c00381
•Featured on the journal's cover; see, https://pubs.acs.org/pb-assets/images/_journalCovers/orlef7/orlef7_v022i015-3.jpg?0.7175240075877755
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47. Bihani, M.;† Ansari, T. N.;† Finck, L.; Bora, P. P.; Jasinski, J. B.; Pavuluri, B.; Leahy, D. K.; Handa, S. "Ultrasmall Pd Nanoparticles in Aqueous Micelles for Scalable α-Arylation of Nitriles: Surprising Formation of Carbanions." ACS Catal., 2020, 10, 6816. https://doi.org/10.1021/acscatal.0c01196
† these authors contributed equally.
•Highlighted in C&E News; see, https://cen.acs.org/environment/green-chemistry/organic-chemists-micellar-chemistry-offers/98/i22?utm_source=LatestNews&utm_medium=LatestNews&utm_campaign=CENRSS
•Highlighted in SYNFACTS, https://doi.org/10.1055/s-0040-1706757
•Featured on the journal's cover; see, https://pubs.acs.org/pb-assets/images/_journalCovers/accacs/accacs_v010i012-2.jpg?0.524636930271761
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46. Sharma, S.; Das, J.; Handa, S. "A Glimpse on Green Chemistry Practices in the Pharmaceutical Industry." ChemSusChem, 2020, 13, 2859. https://doi.org/10.1002/cssc.202000317
•Designated as a VIP article
•Featured on the journal's front cover; https://chemistry- europe.onlinelibrary.wiley.com/doi/epdf/10.1002/cssc.202001205
•This article also appears in: Hot Topic: C-C Coupling, Wiley
•Featured with Authors Profile, https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/cssc.202001204
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2019
45. Wilfried, B.; Gallou, F.; Handa, S.; Tang, W. "Sustainable and Affordable Chemistry." ChemCatChem, 2019, 11, 5660. https://doi.org/10.1002/cctc.201901986
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44. Duong, U. T.; Gade, A.; Plummer, S.; Gallou, F.; Handa. S. "Reactivity of Carbenes in Aqueous Nanomicelles Containing Palladium Nanoparticles." ACS Catal., 2019, 9, 10963. https://doi.org/10.1021/acscatal.9b04175.
•Highlighted in SYNFACTS, 2020, 16, 323.
43. Ansari, T.; Taussat, A.; Clark, A.; Nachtegaal, M.; Plummer, S.; Gallou, F.; Handa, S. "Insights on Bimetallic Micellar Nanocatalysis for Buchwald-Hartwig Aminations."ACS Catal., 2019, 9, 10389. DOI: 10.1021/acscatal.9b02622.
•Highlighted in C&EN
•Highlighted in SYNFACTS, 2020, 16, 197.
42. Bihani, M.; Bora, P. P.; F.; Jasinski, J. B.; Nachtegaal Maarten, M.; Gallou, Handa, S. "Microballs containing Ni(0)Pd(0) nanoparticles for highly selective micellar catalysis in water." ACS Catal., 2019, 9, 7520.
•Highlighted in SYNFACTS, 2019, 15, 1293.
41. Smith, J. D.; Jamhawi, A. M.; Je, J.; Advincula, R.; Gallou, F.; Liu, J.; Handa, S. "Organic polymer with dual chromophores and fast charge transfer properties for sustainable photocatalysis." Nature Communications. 2019, 10, 1837.
•Nature Communications Editors' Highlighted Article for Energy Materials
40. Bora, P. P.; Bihani, M. B.; Plummer, S., Gallou, F.; Handa, S. "Shielding effect of micelle for highly effective and selective monofluorination of indoles in water." ChemSusChem, 2019, 12, 3037.
39. Takale, B.; Thakore, R.; Handa, S.; Gallou, F.; Reilly, J.; Lipshutz, B. "A new, substituted palladacycle for ppm level Pd-catalyzed Suzuki-Miyaura cross-couplings in water." Chem. Sci., 2019, 10, 8825.
38. Handa, S.;*Jin, B.; Bora, P. P.; Wang, Y.; Zhang, X.; Gallou, F.; Reilly, J.; Lipshutz, B. H.* "Sonogashira couplings catalyzed by Fe nanoparticles containing ppm levels of reusable Pd, under mild aqueous micellar conditions." ACS Catal. 2019, 9, 2423.
37. Bora, P.; Handa, S. "Imides in Rhodium Catalysis." Invited Book Chapter for Imides: Medicinal, Agricultural, Synthetic Applications and Natural Products Chemistry, 2019, in production, Elsevier publisher.
36. Ansari, T. N.; Handa, S. "Micelle-Enabled Cross-Couplings in Water - A Technology Relevant to Industry." Invited Book Chapter for Organometallic Chemistry in Industry, 2019, in production, Wiley VCH.
35. Handa, S.; Smith, J. D. “Photoredox catalysis with porous polyemrs through irradiation of a catalyst face not in contact with the reaction mixture.” Application assigned USSN 62/723,697.
2018
34. Handa, S.;* Ibrahim, F.; Ansari, T.; Gallou, F. "π-Allylpalladium species in micelles of FI-750-m for sustainable and general Suzuki-Miyaura couplings of unactivated quinoline systems in water." ChemCatChem, 2018, 9, 4229.
•Featured on the journal's front cover.
33. Smith, J. D.; Ansari, T. N.; Andersson, M. P.; Dongari, Y.; Ibrahim, F.; Liang, S.; Hammond, G. B.; Gallou, F.; Handa. S. “Micelle-enabled clean and selective sulfonylation of polyfluoroarenes in water under mild conditions.” Green. Chem. 2018, 20, 1784.
•This work was featured on the journal's back cover.
32. Landstrom, E. B.; Handa, S.;Aue, D. H.; Gallou, F.; Lipshutz, B. H. "EvanPhos: a ligand for ppm level Pd-catalyzed Suzuki–Miyaura couplings in either organic solvent or water." Green Chem. 2018, 20, 2436.
31. Finck, L.; Brals, J.; Pavuluri, B.; Gallou, F.; Handa, S. “Micelles-enabled photo-assisted selective oxyhalogenation of alkynes in water under mild conditions.” Invited from J. Org. Chem. 2018, 83, 7366.
*published with a high school student and invited article for a special issue on organic and biocompatible transformations in aqueous media.
30. Lu, Z.; Jasinski, J. B.; Handa S.*; Hammond, G. B*. "Recyclable cellulose-palladium nanoparticles for clean cross-coupling chemistry." Org. Biomol. Chem. 2018, 16, 2748.
29. Handa, S.*; Smith, J. D.; Zhang, Y.; Gallou, F.; Lipshutz, B. H. “Sustainable, copper-free HandaPhos-ppm palladium technology for sonogashira couplings in water under mild conditions.” Org. Lett. 2018, 20, 542.
28. Bihani, M.; Ansari, T.; Handa, S. Curr. "The magical but endangered metal: searching for sustainable palladium catalysis." Opin. Green Sustainable Chem. 2018, 11, 45.
2017
27. Brals, J.; Smith, J. D.; Ibrahim, F.; Gallou, F.; Handa, S. “Micelle-enabled palladium catalysis for convenient sp2-sp3 coupling of nitroalkanes with aryl bromides in water under mild conditions.” ACS Catal. 2017, 7, 7245.
26. Smith, J. D.; Gallou, F.; Handa, S. “Organometallic catalysis and sustainability: From origin to date.” (invited) Johnson-Metthey Tech. Rev., 2017, 16, 231.
25. Klumphu, P.; Camille D.; Zhang, Y.; Handa, S.;* Gallou, F; Lipshutz, B. H. "Micellar catalysis-enabled sustainable ppm Au-catalyzed reactions in water at room temperature." Chem. Sci. 2017, 8, 6354. (*corresponding authors)
24. Isley, N. A.; Wang, Y.; Gallou, F.; Handa, S.; Aue, D. H.; Lipshutz, B. H. “A micellar catalysis strategy for Suzuki–Miyaura cross-couplings of 2-pyridyl MIDA boronates: No copper, in water, very mild conditions.” ACS Catal. 2017, 7, 8331.
23. Gabriel, C. M.; Parmentier, M.; Riegert, C.; Lanz, M.; Handa, S.; Lipshutz, B. H.; Gallou, F. “Sustainable and scalable Fe/ppm Pd nanoparticle nitro group reductions in water at room temperature.” Org. Process. Res. Dev. 2017, 21, 247.
22. “Phosphorous ligands and methods of use.” Lipshutz, B. H.; Handa, S. US 2017/0362263 A1
21. “Fe nanoparticles with ppm contents of Pd, Cu and/or Ni, and reactions in water catalyzed by them.” Lipshutz, B. H.; Handa, S. WO 2017106426 A1 20170622.
20. “Biaryl ligands for transition metal-catalyzed reactions.” Lipshutz, B. H.; Handa, S. PCT International Patent Application Serial No. PCT/US17/58946, filed October 30, 2017.
19. “Oxaphosphole ligands for cross-coupling reactions.” Lipshutz, B. H.; Handa, S. PCT International Patent Application Serial No. PCT/US17/58928, filed October 30, 2017.
2016
18. Lipshutz, B. H.; Gallaou, F.; Handa, S. “The evolution of solvents in organic chemistry.” ACS Sustainable Chem. Eng. 2016, 4, 5838.
17. Handa, S;* Smith, J. D.; Hageman, M. S.; Gonzalez, M.; Lipshutz, B. H.* “Synergistic and selective copper/ppm Pd-catalyzed Suzuki-Miyaura couplings: in water, mild conditions, with recycling.” ACS Catal. 2016, 16, 8179. (*corresponding authors)
16. Feng, J.; Handa, S.;* Gallou, F.; Lipshutz, B. H. “Safe and selective nitro group reductions catalyzed by sustainable and recyclable Fe/ppm Pd nanoparticles in water at room temperature.” Angew. Chem., Int. Ed. 2016, 128, 9125. (*corresponding authors)
15. Handa, S.; Andersson, M. P.; Fabrice, G; Reilly, J.; Lipshutz, B. H. “HandaPhos. A general ligand enabling sustainable ppm levels of palladium catalysis in water at room temperature.” Angew. Chem., Int. Ed. 2016, 55, 4914.
Hot article
Featured on i) a journal’s front cover. DOI: 10.1002/anie.201510570
ii) C&En News: http://cen.acs.org/articles/94/i10/Phosphine-ligand-provides-new-low.html
iii) Synfacts, DOI: 10.1055/s-0035-1562001
iv) Org. Process. Res. Dev., DOI: 10.1021/acs.oprd.6b00149
14. “Nano-to-nano Fe/ppm Pd catalysis of Suzuki-Miyaura cross-coupling reactions in water.” Lipshutz, B. H.; Handa, S. US2016/0339418/A1
13. Ruch, A. A.; Handa, S.; Kong, F.; Nesterov, V. N.; Pahls, D. R.; Cundari, T. R.; Slaughter, L. M. “Competing amination and C-H arylation pathways in Pd/xantphos-catalyzed transformations of binaphthyl triflates: switchable routes to chiral amines and helicene derivatives.” Org. Biomol. Chem. 2016, 14, 8123.
2015
12. Handa, S.; Fabrice G.; Lipshutz, B. H. “Sustainable Fe/ppm Pd nanoparticle catalysis of Suzuki-Miyaura cross-coupling reactions in water.” Science, 2015, 349, 1087.
Featured on i) C&En News: http://cen.acs.org/articles/93/i35/Little-Palladium-Does-Lot-Cross.html ii) UCSB current, science & techonolgy:
ii) Chemical Processing: http://www.chemicalprocessing.com/articles/2015/ecofriendly-catalyst-saves-palladium/
iii) Science Daily: http://www.sciencedaily.com/releases/2015/09/150922150100.htm
iv) Org. Process. Res. Dev. DOI: 10.1021/acs.oprd.5b00336
11. Handa, S.; Slack, E. D.; Lipshutz, B. H. “Nano-nickel catalyzed Suzuki-Miyaura cross-couplings in water.” Angew. Chem., Int. Ed. 2015, 54, 11994.
10. Handa, S.; Subramanium, S. S.; Tanski, J. M.; Ruch, A. A.; L. M. “ Ligand- and Brønsted acid/base-switchable reaction pathways in gold(I)-catalyzed cycloisomerizations of allenoic acids.” Org. Biomol. Chem. 2015, 13, 3936.
2014
9. Handa, S.; Lippincott, D. J.; Aue, D. H.; Lipshutz, B. H. “Asymmetric gold-catalyzed lactonizations in water at room temperature.” Angew. Chem., Int. Ed. 2014, 53, 10658.
8. Handa, S.; Fennewald, J. C.; Lipshutz, b. H.; “Aerobic oxidation in nanomicelles of aryl alkynes, in water at room temperature.” Angew. Chem., Int. Ed. 2014, 53, 3432.
Before 2013
7. Nanayakkara, Y. S.; Woods, R.; Breitbach, Z. S.; Handa, S.; Slaughter, L. M.; Armstrong, D. W. “Enantiomeric separation of isochromene derivatives by hplc using cyclodextrin based (cyclobond) stationary phases and principal component analysis of the retention data”. J. Chromatogr. A. 2013, 30, 94.
6. Handa, S; Slaughter, L. M. “Access to 2’-substituted binaphthyl mono-alcohols via complementary nickel-catalyzed kumada coupling reactions under mild conditions: key role of a P, O ligand” J. Org. Chem. 2013, 78, 5694.
5. Singh, P; Raj, R; Bhargava, G; Hendricks, D T.; Handa, S.; Slaughter, L. M.; Kumar, V. “β-Lactam synthon-interceded diastereoselective synthesis of functionalized octahydroindole-based molecular scaffolds and their in vitro cytotoxic evaluation.” Eur. J. Med. Chem. 2012, 58, 513.
4. Owusu, M. O.; Handa, S.; Slaughter, L. M. “Chugaev-type bis(acyclic diaminocarbenes) as a new ligand class for the palladium-catalyzed Mizoroki-Heck reaction.” App Organomet. Chem. 2012, 26, 712.
3. Handa, S.; Slaughter, L. M. “Enantioselective alkynylbenzaldehyde cyclizations catalyzed by chiral gold(I) acyclic diaminocarbene complexes containing weak Au-pi interaction.” Angew. Chem. Int. Ed. 2012, 51, 2912.
Designated as a Very Important Paper (top 5%)
Featured on i) journal back cover, DOI: 10.1002/anie.201109229
ii) Angewandte Chemie Highlights, DOI: 10.1002/anie.201200739
iii) Synfacts, DOI: 10.1055/s-0031-1290856
iv) Chem Cat Chem, DOI: 10.1002/cctc.201200224
2. Subramanium, S. S.; Handa, S.; Miranda, A. J.; Slaughter, L. M. “Simple silver salts and palladium bis(N-heterocyclic carbene) complexes as complementary catalysts for the Nazarov cyclization.” ACS Catalysis. 2011, 1, 1371.
1. Raj, R.; Mehra, V.; Singh, P.; Kumar, V.; Bhargava, G.; Mahajan, M. P.; Handa, S.; Slaughter, L. M. “β-Lactam-synthon-interceded, facile, one-pot, diastereoselective synthesis of functionalized tetra/octahydroisoquinolone derivatives” Eur. J. Org. Chem. 2011, 2011, 2697.